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Thursday, December 2, 2021

A vaccine against Valley fever finally works-for dogs

In addition, since Valley Fever is a regional disease, doctors need regional knowledge to recognize its existence. People who work in New York City may not think about it like doctors in Las Vegas. To make matters worse, only 26 states (plus Washington, D.C.) list it as something that must be notified to public health authorities. Although California is one of the most severely affected states, second only to Arizona, California’s wealthy scientific and technological workers rarely suffer from this disease. The main victims are those who are already immunocompromised or work outdoors or exposed to warm, windy and dusty environments: not only farm workers, but also contractors, road workers, excavators and layout subdivisions House builder.

Others at risk: military personnel assigned to the southwest base and winter vacationers from the cold northern states, they have all returned to places where doctors are unlikely to detect the disease.As i wrote for Scientific american This summer, in 2018, CDC epidemiologists cleaned up the disease nationwide and found cases In 14 states Most are located along the Canadian border-these places are too cold for infection to occur there. After unlocking the patients’ past travel records, investigators realized that these people had been infected somewhere in the south and brought the fungus home.

Thompson said: “If we develop a vaccine, then people living in endemic areas must be the starting point for people with weakened immune functions.” “But it may also become the backbone of travel medicine. Before visiting certain locations, consider travel advice. It will be fun-although I don’t think the states will remind people to get vaccinated before they visit.”

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Climate Change Connection Guide

The world is getting warmer and the weather is getting worse. This is all you need to know about what humans can do to stop the destruction of the planet.

Valley fever is Estimated cost At 3.9 billion U.S. dollars per year, it is estimated that a vaccine can save 1.5 billion U.S. dollars in healthcare costs each year. However, as climate change is expanding Valley Fever as an area at risk of infection, the cost and the urgency of obtaining vaccines will almost certainly increase. The fungus responds to temperature and humidity: it needs a warm environment to thrive, and in humid conditions, it stays still in the soil.But as climate warming intensifies, new areas will be Coccididae, And changing rainfall patterns mean that the area where it starts to grow will become dry enough that it will split and drift. There is already a known fragile area in the center of Washington State, which was previously thought to be too cold for fungi. In 2010, three people there contracted Valley Fever, including a construction worker and a teenager ranting on the ATV.

In 2019, Morgan Gorris, an earth system scientist at Los Alamos National Laboratory, used temperature and rainfall data to more accurately estimate the epidemic of valley fever based on the known behavior of the fungus in the humidity and warmth range. place.Using these findings and combining them with different climate warming predictions, she simulated how Valley fever may expand Under different greenhouse gas emission scenarios. Under the most severe warming scenario (a global increase of nearly 9 degrees Fahrenheit), the area where this disease may become endemic will double by 2100, covering 17 states, including Idaho, Wyoming, and Montgomery. States, Nebraska, and Dakota. The model predicts that the number of cases will increase by half. In another analysis based on this work, she estimated that by 2100, the annual loss caused by valley fever in the United States will reach 18.5 billion U.S. dollars.

The looming bill and the illness and death behind it may be the best reason to develop a vaccine. “Climate change will exacerbate ongoing threats and trigger new threats,” Goris said. “We will need resources in the future to adequately combat emerging diseases. Having a vaccine that addresses the risk of valley fever will allow us to free up resources to address other climate change issues, especially those related to human health.”

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